The LEX diagnostic system consists of a low cost reader working with disposable cartridges. The pair combines & physically contains every step of the process including:
- eluting the sample swab
- extracting genetic material
- reverse transcription
- amplifying DNA
- results measurement and readout
A yes/no result for up to 3 targets (and a control) is presented to the user on a screen and more detailed data for further clinical analysis is provided over an encrypted wireless interface.
Containing the infectious material
The product is focussed on low resource clinical settings and designed for use with minimal training. As a result we have eliminated the common practice of swilling the swab in an open bath of elution fluid. This eliminates a major source of process variability and greatly reduces the risk of surface contamination from spillage.
Rapid time to answer, every time
In most cases, most people are free of virus when tested so time to a reliable negative result drives clinical usability. Many tests are able to offer a fast time to a positive answer when the sample is full of virus but must be run much longer to establish that a patient is virus free. LEX technology drives the amplification process so fast that there is little time difference between a positive and negative answer. Both are provided in less than 5 minutes.
This is important for influenza & RSV testing in a doctors office, and even more so for testing in both the early and late stages of a virus pandemic such as COVID19.
The LEX device is still in development with clinical trials expected to start in the autumn. The first test to be offered will be Influenza A&B followed by Covid19 and RSV. Our open platform strategy makes the development of many new and novel tests likely in the future.
Cheap, fast and portable
The LEX system has been designed from the start to have the speed and convenience of the existing antigen tests but the accuracy of molecular diagnostics. The combination of high speed and low power requirement enables a large number of tests to be run on a standard rechargeable battery for use in the field or direct from the doctor’s desk drawer. The charge port is a standard micro USB connector which means battery life can be extended using the familiar USB battery power packs.